GDI2 Antibody, KO Validated | 23-690

GDI2 Antibody, KO Validated | 23-690 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 296-445 of human GDI2 (NP_001485.2) .

Research Area: Signal Transduction

Tested Application: WB, IF

Application: WB: 1:200 - 1:3000
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: HT-29

Positive Control 2: A-549

Positive Control 3: HepG2

Positive Control 4: U-87MG

Positive Control 5: Mouse spleen

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 51kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GDI2, RABGDIB, HEL-S-46e

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.