223

GDPD5 Antibody | 7739

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SKU:
223-7739-GEN
NULL341.00 - NULL647.00

Description

GDPD5 Antibody | 7739 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Chicken: (94%)

Immunogen: GDPD5 antibody was raised against an 18 amino acid peptide near the amino terminus of human GDPD5.
The immunogen is located within the first 50 amino acids of GDPD5.

Research Area: Stem Cell

Tested Application: E, WB, IHC-P, IF

Application: GDPD5 antibody can be used for detection of GDPD5 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.

Positive Control 1: Cat. No. 1405 - Mouse Kidney Tissue Lysate

Positive Control 2: Cat. No. 10-401 - Human Kidney Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 40, 67 kDa
Observed: 52 kDa

Validation: N/A

Isoform: N/A

Purification: GDPD5 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: GDPD5 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: GDPD5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: GDPD5 Antibody: GDE2, PP1665, GDE2, PP6037, PP9363, UNQ1850/PRO3580, Glycerophosphodiester phosphodiesterase domain-containing protein 5, Glycerophosphodiester phosphodiesterase 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth (2, 3) . Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer (4) .

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