GFI1B Polyclonal Antibody | E-AB-17998

GFI1B Polyclonal Antibody | E-AB-17998 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: GFI 1B, gfi1b, GFI1B protein, GFI1B, Growth factor independent 1B protein, Growth factor independent 1B transcription repressor, Growth factor independent protein 1B, OTTHUMP00000022443, OTTHUMP00000022444, OTTHUMP000000235527, Potential regulator of CDKN1A, Potential regulator of CDKN1A translocated in CML, Translocated in CML, Zinc finger protein Gfi-1b

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Epigenetics and Nuclear Signaling

Background: This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.GFI1B (Growth Factor Independent 1B Transcriptional Repressor) is a Protein Coding gene. Diseases associated with GFI1B include Bleeding Disorder, Platelet-Type, 17 and Gray Platelet Syndrome. Among its related pathways are NF-kappaB Signaling. GO annotations related to this gene include RNA polymerase II transcription factor binding. An important paralog of this gene is GFI1.

Concentration: 1.14 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human GFI1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A