GFRA4 Antibody (Center) [APR31094G]

GFRA4 Antibody (Center) [APR31094G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.

Cellular Localisation: [Isoform GFRalpha4a]: Cell membrane; Lipid- anchor, GPI-anchor [Isoform GFRalpha4c]: Secreted.

Molecular Weight: 31670

Clone: Polyclonal

Gene Name: GFRA4

Gene ID: 64096

Function: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.

Summary: Tissue Location: Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor, GFRA4