GHR polyclonal Antibody | BS90603

GHR polyclonal Antibody | BS90603 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: GHR (growth hormone receptor) binds growth hormone (GH), which is produced by the anterior pituitary and regulates body growth and other metabolic processes. GHR is an integral membrane protein and a member of the cytokine receptor family. A common characteristic of the cytokine receptor family is having soluble forms of the protein. The soluble form of GHR is GH-binding protein (GHBP), which is generated by the proteolytic cleavage of the extracellular domain of GHR (2-4) . Reduced levels of GHBP are associated with GH insensitivity syndrome (GHIS) (2,4) . GHR has been shown to be transcribed via at least two different promoters, resulting in GHR 1A and GHR 1B. Both GHR 1A and 1B are expressed in liver, whereas GHR 1B is also expressed in muscle, uterus, and ovary tissues.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Growth hormone receptor polyclonal Antibody detects endogenous levels of Growth hormone receptor protein.

Molecular Weight: 71 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GH receptor, GH-binding protein, GHBP, GHR, GH receptor, GH-binding protein, GHBP, GHBP, included, GHR, GHR, Growth hormone binding protein, Growth hormone receptor, Growth hormone receptor precursor, Growth hormone-binding protein, Growth hormone-binding protein, included, Increased responsiveness to growth hormone, included, Serum binding protein, Serum-binding protein, Somatotropin receptor,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: