Description
GITR Antibody | 36-215 | Gentaur UK, US & Europe Distribution
Host: Rat
Reactivity: Human
Homology: N/A
Immunogen: Recombinant human GITR.
Research Area: Cancer, Immunology
Tested Application: E, Flow
Application: ELISA: (direct and indirect: 1:5, 000-1:10, 000) . Flow Cytometry: (1:1, 000) . Optimal conditions must be determined individually for each application.
Specificiy: Recognizes human GITR. Does not cross-react with mouse GITR.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Condition: Stable for at least 6 months after receipt when stored at -20˚C.
Alternate Name: Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.