GLO1 polyclonal Antibody | BS90577

GLO1 polyclonal Antibody | BS90577 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500-1:2,000 ICC:1:100-1:500 IHC:1:100-1:500 FC:1:50-1:100

Background: The glyoxal pathway plays a role in the detoxification of glucose degradation products (GDP) . Glyoxalase I (GLO1), a member of the glyoxalase family, is effective in eliminating GDP. Overexpression or silencing of Glyoxalase I in mice brain suggests an association between Glyoxalase I and anxiety. Glyoxalase I has three isoforms generated from two alleles in the genome which forms two homodimers and one heterodimer, each subunit binding one zinc ion. Research demonstrates that GLO1 gene expression is induced in colon carcinoma. Both an insulin response element (IRE), and a zinc metal response element (MRE) in the promoter region of the GLO1 gene have been identified.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GLO1 polyclonal Antibody detects endogenous levels of GLO1 protein.

Molecular Weight: 21 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Glx I, GLO1, Aldoketomutase, glo1, GLOD1, Glx I, GLYI, glyoxalase domain containing 1, Glyoxalase I, Ketone aldehyde mutase, Ketone-aldehyde mutase, Lactoyl glutathione lyase, Lactoylglutathione lyase, LGUL, Methylglyoxalase, S D lactoylglutathione methylglyoxal lyase, S-D-lactoylglutathione methylglyoxal lyase,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: