GLPG-1690 | B1850

GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).

GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).

B1850 | GLPG-1690 DataSheet

Alternate Name/Synonyms: 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1628260-79-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₃₀H₃₃FN₈O₂S

Molecular Weight: 588.7

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective autotaxin inhibitor

MDL Number: N/A

PubChem CID: 90420193

SMILES: CCC1=C(N2C=C(C=C(C2=N1)C)N3CCN(CC3)CC(=O)N4CC(C4)O)N(C)C5=NC(=C(S5)C#N)C6=CC=C(C=C6)F

InChi: InChI=1S/C30H33FN8O2S/c1-4-24-29(35(3)30-34-27(25(14-32)42-30)20-5-7-21(31)8-6-20)39-15-22(13-19(2)28(39)33-24)37-11-9-36(10-12-37)18-26(41)38-16-23(40)17-38/h5-8,13,15,23,40H,4,9-12,16-18H2,1-3H3

InChi Key: REQQVBGILUTQNN-UHFFFAOYSA-N