Glutamate receptor 1 polyclonal Antibody | BS90585

Glutamate receptor 1 polyclonal Antibody | BS90585 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC IP

Application Range: WB:1:1,000-1:2,000 IHC:1:50-1:200

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Glutamate receptor 1 polyclonal Antibody detects endogenous levels of Glutamate receptor 1 protein.

Molecular Weight: 92 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GluR-1, GluA1,, GLUR 1, GLUR A, AMPA 1, AMPA selective glutamate receptor 1, AMPA-selective glutamate receptor 1, GluA1, GLUH1, GluR K1, GluR-1, GluR-A, GluR-K1, GLUR1, GLURA, GluRK1, Glutamate receptor 1, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic, Glutamate receptor, ionotropic, AMPA 1, Gria1, GRIA1, HBGR1, MGC133252, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: