GMPS Antibody | 22-346

GMPS Antibody | 22-346 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 394-693 of human GMPS (NP_003866.1) .

Research Area: Other

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: MCF-7

Positive Control 2: SKOV3

Positive Control 3: HL-60

Positive Control 4: U-251MG

Positive Control 5: Mouse heart

Positive Control 6: Mouse kidney

Molecular Weight: Observed: 80kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GMPS,

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1) , which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.