GNAI3 Antibody, KO Validated | 14-905

GNAI3 Antibody, KO Validated | 14-905 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-354 of human GNAI3 (NP_006487.1) .

Research Area: Cell Cycle, Neuroscience, Signal Transduction

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: LO2

Positive Control 2: MCF-7

Positive Control 3: HL-60

Positive Control 4: HT-1080

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 45kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: Gai3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.