GNAO1 polyclonal Antibody | BS7367

GNAO1 polyclonal Antibody | BS7367 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GNAO1 polyclonal Antibody detects endogenous levels of GNAO1 protein.

Molecular Weight: ~40 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: DKFZp686O0962; G alpha o; G protein alpha 0; Galphao; GNAO 1; GNAO; GNAO_HUMAN; GNAO1; Go alpha; Guanine nucleotide binding protein (G protein) alpha activating activity polypeptide O; Guanine nucleotide binding protein alpha activating polypeptide; Guanine nucleotide binding protein G (o) subunit alpha; Guanine nucleotide-binding protein G (o) subunit alpha;

Immunogen: Recombinant full length Human GNAO1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: