Goat Anti-Human P53 Polyclonal Antibody | AB0065

Goat Anti-Human P53 IgG Polyclonal Antibody | AB0065 | Antibodies

Overview: Goat polyclonal antibody to P53. This protein reacts to diverse cellular stresses to regulate target genes that induce apoptosis, senescence, cell cycle arrest, DNA repair, or changes in metabolism. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is assumed to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumour suppressor.

Other Names: BCC7, LFS1 and TRP53 antibody.

Other Names: BCC7, LFS1 and TRP53 antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: Anti-P53

Accession Number: ENSG00000141510

Host Species: Goat

Immunogen Species: Human

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within residues 280 aa to the C-terminus of human P53 produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: Detects endogenous levels of P53 by Western blot.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB, IF

Concentration/Dilution: WB:1:500-1:2,000, IF:1:50-1:250

Storage: N/A

References: 1. Ferreira JV, Rosa Soares A, Ramalho JS, et al. PLoS One. 2019 Oct. PMID:31613922