gp120 Antibody | 8677

gp120 Antibody | 8677 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: HIV-1

Homology: N/A

Immunogen: gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.

Research Area: Infectious Disease

Tested Application: E, WB

Application: gp120 antibody can be used for Western blot at 1 - 2 μg/mL.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 120 kDa
Observed: 120 kDa

Validation: N/A

Isoform: N/A

Purification: gp120 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: gp120 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: gp120 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: gp120 Antibody: Envelope glycoprotein gp160

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.