GPHN Antibody | 23-666

GPHN Antibody | 23-666 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 520-769 of human GPHN (NP_065857.1) .

Research Area: Cell Cycle, Neuroscience

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:100 - 1:200

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: Mouse brain

Positive Control 3: Mouse liver

Positive Control 4: Rat brain

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 103kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GPHN, GEPH, GPH, GPHRYN, KIAA1385, HKPX1, MOCODC

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.