GPM6A Polyclonal Antibody | E-AB-10938

GPM6A Polyclonal Antibody | E-AB-10938 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: GPM6A, GPM6A, M6a, Neuronal membrane glycoprotein M6-a, Neuronal membrane glycoprotein M6-a,

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Neuroscience

Background: Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human GPM6A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 31 kDa

Molecular Weight(Observed): N/A