GPN1 Antibody (C-term) [APR31437G]

GPN1 Antibody (C-term) [APR31437G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-352 amino acids from the C-terminal region of human GPN1.

Cellular Localisation: Cytoplasm. Nucleus Note=Shuttles between the nucleus and the cytoplasm

Molecular Weight: 41740

Clone: Polyclonal

Gene Name: GPN1 {ECO:0000303|PubMed:20855544, ECO:0000312|HGNC:HGNC:17030}

Gene ID: 11321

Function: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307) . May act at an RNAP assembly step prior to nuclear import (PubMed:21768307) . Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375) . May be involved in nuclear localization of XPA (PubMed:11058119) .

Summary: Tissue Location: Expressed ubiquitously.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: GPN-loop GTPase 1, 365-, MBD2-interacting protein, MBDin, RNAPII-associated protein 4, XPA-binding protein 1, GPN1 {ECO:0000303|PubMed:20855544, ECO:0000312|HGNC:HGNC:17030}