GPR112 polyclonal Antibody | BS60350

GPR112 polyclonal Antibody | BS60350 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: G protein-coupled receptors (GPRs or GPCRs), also known asseven transmembrane receptors, heptahelical receptors or 7TMreceptors, aremembers of the largest protein family and play a role in many differentstimulus-response pathways. G protein-coupled receptors mediate extracellularsignals into intracellularsignals (G protein activation) . Theyrespond to awide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usuallyintegralseven passmembrane proteins with some conserved amino acid regions. GPR112 (G protein-coupled receptor 112) is a 3,080 amino acid multi-pass membrane protein that belongsto the G-protein coupled receptor 2 family and LN-TM7 subfamily. Localizing to cell membrane, GPR112 is highly expressed in normal enterochromaffin cells, aswell as neuroendocrine and primarylivercarcinoma. GPR112 contains one GPS domain andmayfunction as an orphan receptor.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GPR112 polyclonal Antibody detects endogenous levels of GPR112 protein.

Molecular Weight: ~ 333 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Probable G-protein coupled receptor 112; GPR112

Immunogen: A synthetic peptide corresponding to residues in Human GPR112.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: