GPR124 Polyclonal Antibody | ABP54458

GPR124 Polyclonal Antibody | ABP54458 | Gentaur UK, US & Europe Distribution

Immunogen: Synthesized peptide derived from the C-terminal region of human GPR124 at AA rangle: 1120-1200

Product Category: Protein

Application: Protein General Reagents

Product Type: Primary Antibody

Host: Rabbit

Reactivity: Human, Mouse

Application: WB, IF, ELISA

Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000) . Not yet tested in other applications.

Clonality: Polyclonal

Isotype: Rabbit IgG

Formulation: Liquid solution

Kit Component: N/A

Concentration: 1 mg/ml

Storage Buffer: PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping Condition: Gel pack with blue ice.

Background: ADGRA2 (Adhesion G Protein-Coupled Receptor A2) is a Protein Coding gene. Among its related pathways are Integrins in angiogenesis. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRA1. ndothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity) . Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity) . Has a major role in establishing the blood-brain barrier (By similarity) . Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed: 16982628) .

Alternative Names: GPR124; KIAA1531; TEM5; G-protein coupled receptor 124; Tumor endothelial marker 5

Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.