GPR217 polyclonal Antibody | BS62478

GPR217 polyclonal Antibody | BS62478 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1000

Background: In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: SCML2 polyclonal Antibody detects endogenous levels of SCML2 protein.

Molecular Weight: ~ 77,93 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Sex comb on midleg-like protein 2; SCML2

Immunogen: Synthetic peptide, corresponding to Human SCML2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .

Pathway: