GPR224 polyclonal Antibody | BS62603

GPR224 polyclonal Antibody | BS62603 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat,Mouse

Application: WB

Application Range: WB: 1:500~1:1000

Background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FTO polyclonal Antibody detects endogenous levels of FTO protein.

Molecular Weight: ~ 58 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; U6 small nuclear RNA (2'-O-methyladenosine-N (6) -) -demethylase FTO; U6 small nuclear RNA N (6) -methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N (6) -) -demethylase FTO; m6A (m) -demethylase FTO;mRNA N (6) -methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO; KIAA1752

Immunogen: Synthetic peptide, corresponding to Human FTO.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Vesicle Trafficking presynaptic signaling,