GPT Antibody | 18-825

GPT Antibody | 18-825 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human GPT (NP_005300.1) .

Research Area: Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:200 - 1:1000
IHC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: Mouse liver

Positive Control 2: Mouse lung

Positive Control 3: Mouse intestine

Positive Control 4: Rat liver

Positive Control 5: Rat heart

Positive Control 6: N/A

Molecular Weight: Observed: 55kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GPT, AAT1, ALT1, GPT1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1) ; also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.