GPX4 polyclonal Antibody | BS90597

GPX4 polyclonal Antibody | BS90597 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, Zebrafish

Application: WB IHC

Application Range: WB:1:500-1:2,000 IHC:1:50-1:200

Background: Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8) . GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GPX4 polyclonal Antibody detects endogenous levels of GPX4 protein.

Molecular Weight: 22 kDa Clone number: JU11-31

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PHGPx, GPx-4, GSHPx-4, Glutathione peroxidase 4, GPX 4, GPX-4, GPX4, GPX4, GSHPx-4, MCSP, mitochondrial, PHGPx, Phospholipid hydroperoxidase, Phospholipid hydroperoxide glutathione peroxidase, Phospholipid hydroperoxide glutathione peroxidase mitochondrial, snGPx, snPHGPx, Sperm nucleus glutathione peroxidase,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: