Granzyme B Inhibitor Z-AAD-CH2Cl | 1128

A synthetic peptide that irreversibly inhibits granzyme B activity. The inhibitor is designed as a methyl ester to facilitate cell permeability.

Z-AAD-CMK is a irreversible Granzyme B inhbitor.

1128 | Granzyme B Inhibitor Z-AAD-CH2Cl DataSheet

Alternate Name/Synonyms: Z-AAD-CMK, Granzyme B Inhibitor(chloromethylketone)

Appearance: Liquid

Formulation: DMSO (10 mM)

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: Z-Ala-Ala-Asp(OMe)-CMK

Salt Form: No

Molecular Formula: C₂₀H₂₆ClN₃O₇

Molecular Weight: 455.89

Cell-Permeable?: No

Purity: Single spot by TLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A granzyme B inhibitor

MDL Number: N/A

PubChem CID: 44135188

SMILES: CC(C(=O)NC(CC(=O)OC)C(=O)CCl)NC(=O)C(C)NC(=O)OCC1=CC=CC=C1

InChi: InChI=1S/C20H26ClN3O7/c1-12(19(28)24-15(16(25)10-21)9-17(26)30-3)22-18(27)13(2)23-20(29)31-11-14-7-5-4-6-8-14/h4-8,12-13,15H,9-11H2,1-3H3,(H,22,27)(H,23,29)(H,24,28)

InChi Key: QMNQUIKZKYBZII-UHFFFAOYSA-N