Granzyme B polyclonal Antibody | BS8466

Granzyme B polyclonal Antibody | BS8466 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Granzyme B polyclonal Antibody detects endogenous levels of Granzyme B protein.

Molecular Weight: ~ 27kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Granzyme B; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; Short name=HLP; SECT; T-cell serine protease 1-3E; GZMB; CGL1; CSPB; CTLA1, GRB;

Immunogen: Recombinant full length Human Granzyme B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Actin Dynamics,Regulation of Microtubule Dynamics,Inhibition of Apoptosis,G Protein-coupled Receptors Signaling to MAPK Erk,Mitochondrial Control of Apoptosis,