BW
GRB10 monoclonal Antibody | MB63448
- SKU:
- BW-MB63448
- Availability:
- Usually ships in 5 working days
Description
GRB10 monoclonal Antibody | MB63448 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC, WB
Application Range: WB 1:500, IHC 1:500
Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: growth factor receptor bound protein 10
Molecular Weight: 67.1 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Grb-10; GRB-IR; IRBP; MEG1; RSS
Immunogen: Human recombinant protein fragment corresponding to amino acids 164-415 of human GRB10 (NP_005302) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A