763

GRB2 Polyclonal Antibody | E-AB-61066

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SKU:
763-E-AB-61066-GEN
NULL307.00 - NULL593.00

Description

GRB2 Polyclonal Antibody | E-AB-61066 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2, GRB2

Application: WB, IHC, IF

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human GRB2 (NP_002077.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 20 kDa/25 kDa

Molecular Weight(Observed): 33 kDa

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