GRM1 polyclonal Antibody | BS60765

GRM1 polyclonal Antibody | BS60765 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors) . The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-1, which can form a homodimer acts as a receptor for glutamate. It may also be involved in glutamate activity in the CNS.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GRM1 polyclonal Antibody detects endogenous levels of GRM1 protein.

Molecular Weight: ~ 132 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Metabotropic glutamate receptor 1; mGluR1; GRM1; GPRC1A; MGLUR1

Immunogen: A synthetic peptide corresponding to residues in Human GRM1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: