GRM2 Antibody (C-Term) [APR33609G]

GRM2 Antibody (C-Term) [APR33609G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This GRM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 681-715 amino acids from the human region of human GRM2.

Cellular Localisation: Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite

Molecular Weight: 95568

Clone: Polyclonal

Gene Name: GRM2 (HGNC:4594)

Gene ID: 2912

Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Summary: Tissue Location: Detected in brain cortex (at protein level) . Widely expressed in different regions of the adult brain as well as in fetal brain.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Metabotropic glutamate receptor 2, mGluR2, GRM2, GPRC1B, MGLUR2