Gsh1 Polyclonal Antibody | BS65696

Gsh1 Polyclonal Antibody | BS65696 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Sheep,

Application: WB,

Application Range: WB=1:500-2000

Background: Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Gsh1 Polyclonal Antibody detects endogenous levels of Gsh1 protein.

Molecular Weight: 30 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GS homeo box protein 1; GS homeobox 1; GSH1; GSX1; GSX1_HUMAN; Homeobox protein GSH-1 ; Homeobox protein Gsh1.

Immunogen: KLH conjugated synthetic peptide derived from human Gsh1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: