GSK-2018682 | B1967

GSK-2018682 is a potent sphingosine -1 phosphate receptor (S1PR)-1 agonist; useful for the treatment of multiple sclerosis. GSK-2018682 induces acute, transient and non-symptomatic decreases in heart rate and blood pressure.

GSK-2018682 is a potent sphingosine-1 phosphate receptor (S1PR)-1 agonist; useful for the treatment of multiple sclerosis. GSK-2018682 induces acute, transient and non-symptomatic decreases in heart rate and blood pressure.

B1967 | GSK-2018682 DataSheet

Alternate Name/Synonyms: 4-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-1H-indol-1-yl)butanoic acid

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1034688-30-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₁ClN₄O₄

Molecular Weight: 440.88

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent sphingosine 1 phosphate receptor (S1PR)-1 agonist

MDL Number: N/A

PubChem CID: 24988201

SMILES: CC(C)OC1=C(C=C(C=N1)C2=NC(=NO2)C3=C4C=CN(C4=CC=C3)CCCC(=O)O)Cl

InChi: InChI=1S/C22H21ClN4O4/c1-13(2)30-22-17(23)11-14(12-24-22)21-25-20(26-31-21)16-5-3-6-18-15(16)8-10-27(18)9-4-7-19(28)29/h3,5-6,8,10-13H,4,7,9H2,1-2H3,(H,28,29)

InChi Key: NFIGDBFIDKDNIG-UHFFFAOYSA-N