GSK-2801 | 9553

GSK-2801 is a potent, selective and cell-permeable inhibitor of the BAZ2 family of bromodomain containing proteins. GSK-2801 binds to BAZ2 bromodomains with dissociation constants (KD) of 136 and 257 nM for BAZ2B and BAZ2A, respectively.

GSK-2801 is a potent, selective and cell-permeable inhibitor of the BAZ2 family of bromodomain containing proteins. GSK-2801 binds to BAZ2 bromodomains with dissociation constants (KD) of 136 and 257 nM for BAZ2B and BAZ2A, respectively.

9553 | GSK-2801 DataSheet

Alternate Name/Synonyms: 4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1619994-68-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₁NO₄S

Molecular Weight: 371.54

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent BAZ2 family of bromodomain inhibitor

MDL Number: MFCD26142953

PubChem CID: N/A

SMILES: CC(C1=CC(C2=CC=CC=C2S(=O)(C)=O)=C3C=C(OCCC)C=CN13)=O

InChi: InChI=1S/C20H21NO4S/c1-4-11-25-15-9-10-21-18(14(2)22)13-17(19(21)12-15)16-7-5-6-8-20(16)26(3,23)24/h5-10,12-13H,4,11H2,1-3H3

InChi Key: KHWCPNJRJCNVRI-UHFFFAOYSA-N