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GSK1278863 | B1107

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SKU:
26-B1107-GEN
Availability:
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NULL388.00

Description

GSK-1278863 is a novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (HIF-PHI). Hypoxia-inducible factor−prolyl hydroxylase inhibitors stimulate endogenous EPO synthesis and induce effective erythropoiesis by non-EPO effects.

GSK-1278863 is a novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (HIF-PHI). Hypoxia-inducible factor−prolyl hydroxylase inhibitors stimulate endogenous EPO synthesis and induce effective erythropoiesis by non-EPO effects.

B1107 | GSK1278863 DataSheet

Alternate Name/Synonyms: (1, 3-Dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine; Daprodustat

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 960539-70-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: Yes

Molecular Formula: C₁₉H₂₇N₃O₆

Molecular Weight: 393.44

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor

MDL Number: N/A

PubChem CID: 91617630

SMILES: C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O

InChi: InChI=1S/C19H27N3O6/c23-14(24)11-20-16(25)15-17(26)21(12-7-3-1-4-8-12)19(28)22(18(15)27)13-9-5-2-6-10-13/h12-13,15H,1-11H2,(H,20,25)(H,23,24)

InChi Key: RUEYEZADQJCKGV-UHFFFAOYSA-N

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Additional Information

Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
36 months
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