GUCY1B3 Antibody | 15-956

GUCY1B3 Antibody | 15-956 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GUCY1B3 (NP_000848.1) .

Research Area: Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: Mouse brain

Positive Control 2: Rat lung

Positive Control 3: Rat brain

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 70kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GUCY1B3, GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC) , which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate) . The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.