GYS1 polyclonal Antibody | BS8463

GYS1 polyclonal Antibody | BS8463 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200

Background: Glycogen [starch] synthase belongs to the mammalian/fungal glycogen synthase family of proteins. Two forms of this protein exist, a liver form and a muscle form, both of which have the same function in the glycogen biosynthesis pathway. Glycogen synthase transfers the glycosyl residue from UDP-Glucose to the nonreducing end of å-1,4-glucan. The liver glycogen synthase protein is truncated by 34 amino acids compared to the muscle form. However, these enzymes differ significantly in their amino- and carboxyl-terminal regions. Muscle glycogen synthase serves to fuel muscular activity only and is regulated by muscle contraction and by catecholamines. Liver glycogen synthase mediates blood glucose homeostasis in response to nutritional cues. Defects in the gene encoding liver glycogen synthase results in glycogen storage disease type 0 (GSD0), a rare form of fasting ketotic hypoglycemia.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GYS1 polyclonal Antibody detects endogenous levels of GYS1 protein.

Molecular Weight: ~ 100kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Glycogen [starch] synthase, muscle (EC:2.4.1.11) ; GYS1; GYS

Immunogen: Recombinant full length Human GYS1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Signaling Pathways Activating p38 MAP Kinase,