H3K4me3 | Histone H3, trimethylated lysine 4 (H3K4me3) (10 µg) | AS16 3190-10

H3K4me3 | Histone H3, trimethylated lysine 4 (H3K4me3) (10 µg) | AS16 3190-10 | Gentaur UK, US & Europe Distribution

Immunogen: KLH-conjugated synthetic peptide

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Immunogen affinity purified serum.

Format: Liquid

Tested Application: Chromatin immunoprecipitation (ChIP/ChIP-seq), Dot blot (Dot), ELISA (ELISA), Immunofluorescence (IF), peptide array (PA), Western blot (WB)

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Recommended Dilutions: 1-5 µg/IP (ChIP/ChIP-seq), 1 : 10 000 (Dot), 1 : 100 (ELISA), 1 : 200 (IF), 1 : 2000 (PA), 1 : 1000 (WB)

Molecular weight: N/A

Confirmed Reactivity: Human

Predicted Reactivity: Arabidopsis thaliana, Solanum lycopersicum, Oryza sativa, Populus sp., Zea mays

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. Methylation of histone H3K4 is associated with activation of gene transcription.

Reconstitution: N/A

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Epigenetics/DNA methylation

Research Area: Epigenetics