H4K16ac | Histone H4 (ac Lys16) | AS16 3189

H4K16ac | Histone H4 (ac Lys16) | AS16 3189 | Gentaur UK, US & Europe Distribution

Immunogen: KLH-conjugated synthetic peptide

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Immunogen affinity purified serum.

Format: Liquid

Tested Application: Dot blot (Dot), Chromatin immunoprecipitation (ChIP), Immunofluorescence (IF), Immunohistochemistry (IHC), Western blot (WB)

Related Products: AS16 3187 | Anti-H3K56me1 | Histone H3 (monomethyl Lys56), polyclonal antibodies AS16 3182 | Anti-H3K18me2 | Histone H3 (dimethyl Lys18), rabbit antibodies AS16 3183 | Anti-H3K18me3 | Histone H3 (trimethyl Lys18), rabbit antibodies AS16 3181 | Anti-H3K18me1 | Histone H3 (monomethyl Lys18), rabbit antibodies AS16 3168 | Anti-H3T3pK4me1 | Histone H3 (monomethyl Lys4, p Thr3), rabbit antibodies AS16 3169 | Anti-H3T3pK4me2 | Histone H3 (dimethyl Lys4, p Thr3), rabbit antibodies AS16 3172 | Anti-H3K4me3T6p | H3 (trimethyl Lys4, p Thr6), rabbit antibodiesAS16 3197 | Anti-anti-H3core, monoclonal antibodiesAS15 2855 | Anti-H3 | histone H3, chicken polyclonal antibodiesAS10 710 | Anti-H3 | histone H3, rabbit polyclonal antibodiesAS10 710PRE | H3 | histone H3, pre-immune serum to H3 antibody AS10 710collection of antibodies to epigenetics

Recommended Dilutions: 2-5 µg/million cells (ChIP), 1 : 1000 (Dot), 1 : 100 (IF), 1 : 50 (IHC), 1 : 500-1 : 1000 (WB)

Molecular weight: 15 kDa

Confirmed Reactivity: Human

Predicted Reactivity: Caenorhabditis elegans, Chicken, Drosophila melanogaster, Mouse, Plant, Rat, Xenopus sp.

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine. In particular, acetylation of H4 at Lys16 (H4K16ac) plays a role in transcriptional activation and DNA repair. The protein MOF (MYST1) is the primary enzyme to acetylate K16, along with Gcn5, Esal, ATF2, and Sas2.

Reconstitution: N/A

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Epigenetics/DNA methylation

Research Area: Epigenetics