HACE1 Polyclonal Antibody | E-AB-13286

HACE1 Polyclonal Antibody | E-AB-13286 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: E3 ubiquitin-protein ligase HACE1, HACE 1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, KIAA1320

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Background: HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.

Concentration: 1.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human HACE1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A