HADHB polyclonal Antibody | BS8487

HADHB polyclonal Antibody | BS8487 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HADHB polyclonal Antibody detects endogenous levels of HADHB protein.

Molecular Weight: ~ 51kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Trifunctional enzyme subunit beta, mitochondrial; TP-beta; TP-β; TPβ; 3-ketoacyl-CoA thiolase (EC:2.3.1.16) ; Acetyl-CoA acyltransferase; Beta-ketothiolase; HADHB; MSTP029

Immunogen: Recombinant full length Human HADHB.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: