Description
Hamster Anti-Mouse IL-10 receptor alpha Antibody | 103-M242 | Gentaur UK, US & Europe Distribution
Species: Anti-Mouse
Host / biotech: Hamster
Comment: N/A
Label: N/A
Clone / Antibody feature: (#9E12)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Il10ra; Il10r; CDw210; CDw210a; mIL-10R; AW553859
Isotype: IgG
Application: WB, IHC (P)
Detection Range: N/A
Species Reactivity/Cross reactivity: Mouse
Antigen: Mouse recombinant EC domain of IL-10R
Description: Human and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to mouse IL-10 R. Although human IL-10 has cross-species activities and is active on mouse cells, mouse IL-10 is species-specific in its actions and does not bind to the human IL-10 receptor. The human IL-10 R gene has been mapped to chromosome 11q23.3. Recombinant IL-10 soluble receptor, consisting of the extracellular domain of IL-10 R, binds IL-10 with high affinity in solution and is a potent IL-10 antagonist.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 16154