HAND2 Polyclonal Antibody | E-AB-61488

HAND2 Polyclonal Antibody | E-AB-61488 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HAND2, DHAND2, Hed, Thing2, bHLHa26, dHand

Application: WB, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human HAND2 (NP_068808.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 20 kDa/23 kDa

Molecular Weight(Observed): 26 kDa