HC-II Polyclonal Antibody | ABP54719

HC-II Polyclonal Antibody | ABP54719 | Gentaur UK, US & Europe Distribution

Immunogen: Synthesized peptide derived from the N-terminal region of human HC-II at AA rangle: 10-90

Product Category: Protein

Application: Protein General Reagents

Product Type: Primary Antibody

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB, IHC-P, IF, ELISA

Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000) . Not yet tested in other applications.

Clonality: Polyclonal

Isotype: Rabbit IgG

Formulation: Liquid solution

Kit Component: N/A

Concentration: 1 mg/ml

Storage Buffer: PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping Condition: Gel pack with blue ice.

Background: SERPIND1 belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. SERPIND1 encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.

Alternative Names: SERPIND1; HCF2; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1

Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.