HDAC1 Antibody, KO Validated | 13-098

HDAC1 Antibody, KO Validated | 13-098 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2) .

Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Tested Application: WB, IHC, IF, IP

Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
IF: 1:50 - 1:100
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: HeLa

Positive Control 3: HepG2

Positive Control 4: MCF7

Positive Control 5: Mouse thymus

Positive Control 6: Mouse testis

Molecular Weight: Observed: 62kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: HDAC1 Antibody: HD1, RPD3, GON-10, RPD3L1, Histone deacetylase 1, HD1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.