HEATR1 polyclonal Antibody | BS60792

HEATR1 polyclonal Antibody | BS60792 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: HEATR1 (HEAT repeat containing 1), also known as BAP28, is a 2,144 amino acid nuclear protein involved in nucleolar processing of pre-18S ribosomal RNA. HEATR1 is a member of the HEATR1/UTP10 family and contains one HEAT repeat. The gene encoding HEATR1 is located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HEATR1 polyclonal Antibody detects endogenous levels of HEATR1 protein.

Molecular Weight: ~ 242 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: HEAT repeat-containing protein 1; Protein BAP28; N-terminally processed; HEATR1; BAP28

Immunogen: A synthetic peptide corresponding to residues in Human HEATR1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Notch Signaling,