HECW2 Antibody (Center) [APR31444G]

HECW2 Antibody (Center) [APR31444G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This HECW2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 848-876 amino acids from the Central region of human HECW2.

Cellular Localisation: Cytoplasm. Cytoplasm, cytoskeleton, spindle

Molecular Weight: 175769

Clone: Polyclonal

Gene Name: HECW2

Gene ID: 57520

Function: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487) . Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370) .

Summary: Tissue Location: Predominantly expressed in adult brain, lung and heart.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: E3 ubiquitin-protein ligase HECW2, 632-, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2