Additional Information
Size: |
100 µl |
Target: |
HER2 (pTyr877) |
Conjugate: |
RPE |
Research Area: |
Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Receptor Tyrosine Kinases | Cell Signaling | Growth Factors | EGF | Cancer | Tumor Biomarkers | Oncoproteins |
Alternative Name: |
HER2 Antibody, ERBB2 Antibody, Neu Antibody, ERbB2 Antibody, C erb B2/neu protein Antibody, Neuroblastoma/glioblastoma derived oncogene homolog Antibody, Tyrosine kinase-type cell surface receptor HER2 Antibody, Tyrosine kinase type cell surface rece |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human HER2 around the phosphorylation site of tyrosine 877 (pTyr877). |
Immunogen Species: |
Human |
Applications: |
WB, IHC, IP, ELISA |
Host: |
Rabbit |
Isotype: |
N/A |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:250-1:1000); IHC (1:50-1:150); IP (1-2.5 ug per mg lysate); ELISA (1:5000); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of HER2 protein only when phosphorylated at tyrosine 877 (pTyr877). Detects a band at ~185 kDa. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Plasma Membrane, Cell Membrane, Single-Pass Type I Membrane Protein, Nucleus, Perinuclear Region, Cytoplasm, Cytosol, Endosome, Endosome Membrane, Apical Plasma Membrane, Basolateral Plasma Membrane, Integral Component Of Membrane, Myelin Sheath, Per |
Tissue Specificity: |
Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth. |
Accession Number: |
NP_001005862.1 |
Gene ID: |
2064 |
Swiss-Prot: |
P04626 |
Field of Use: |
For in vitro research use only. |