HEY2 Antibody | 15-901

HEY2 Antibody | 15-901 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1) .

Research Area: Stem Cell, Transcription

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: A-549

Positive Control 2: K562

Positive Control 3: MCF7

Positive Control 4: mouse brain

Positive Control 5: rat heart

Positive Control 6: N/A

Molecular Weight: Observed: 36kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: HEY2, OTTHUMP00000017138, MGC10720, HRT2, HES-related repressor protein 1, HESR2, HERP1, hairy-related transcription factor 2, hairy/enhancer-of-split related with YRPW motif 2, GRL, GRIDLOCK, CHF1, cardiovascular basic helix-loop-helix factor 1, bHLHb32, BHLHB32, HERP

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.