Hippocalcin Antibody (N-term) [APG03031G]

Hippocalcin Antibody (N-term) [APG03031G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This Hippocalcin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human Hippocalcin.

Cellular Localisation: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P84076, ECO:0000269|PubMed:28398555}. Membrane {ECO:0000250|UniProtKB:P84076}; Peripheral membrane protein {ECO:0000250|UniProtKB:P84076} Note=Association with membranes is calcium-dependent (By similarity) Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (PubMed:28398555) {ECO:0000250|UniProtKB:P84076, ECO:0000269|PubMed:28398555}

Molecular Weight: 22427

Clone: Polyclonal

Gene Name: HPCA (HGNC:5144)

Gene ID: 3208

Function: Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels (PubMed:28398555) . May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (By similarity) .

Summary: Tissue Location: Brain specific..

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Neuron-specific calcium-binding protein hippocalcin, Calcium-binding protein BDR-2, HPCA, BDR2