Hirudin | Refludan | IMS01-134-330

Hirudin | Refludan | IMS01-134-330 | Gentaur UK, US & Europe Distribution

Immunogen: purified full length recombinant protein (Refludan®, Hoechst Marion Roussel Inc, )

Host: Chicken

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Purified, total IgY (chicken egg yolk immunoglobulin) in 0.9% NaCl, 0.02% sodium azide.

Format: Liquid

Tested Application: Total, purified IgY

Related Products: Secondary antibodies

Recommended Dilutions: 1 : 1000 (ELISA), 1 : 1000 (WB)

Molecular weight: 7 kDa

Confirmed Reactivity: Hirudin

Predicted Reactivity: Hirudo medicinalis

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: Reactiv against purified hirudine; no reactivity against normal human plasma in ELISA

Background: Hirudin (P01050) is a highly effective and very specific anticoagulant which specifically inhibits formation of fibrin and activation of factors V, VIII and XIII, by forming irreversible, noncovalent 1:1 complexes with alpha-thrombin. Hirudin is a 65 amino acid polypeptide, 7 kDa protein, naturally originating from the medical leech Hirudo medicinalis. It is a very potent thrombin inhibitor. Antibody binding to hirudin inhibits the interaction with alpha-thrombin.

Reconstitution: N/A

Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Immunology

Research Area: Immunology