Histone H1 Polyclonal Antibody | E-AB-31676

Histone H1 Polyclonal Antibody | E-AB-31676 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HIST1H1B, H1F5, Histone H1.5, Histone H1a, Histone H1b, Histone H1s-3, HIST1H1D, H1F3, Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1E, H1F4, Histone H1.4, Histone H1b, Histone H1s-4

Application: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human Histone H1 around the non-phosphorylation site of Thr17.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 23 kDa

Molecular Weight(Observed): 31 28 kDa